Why a Closed Loop Solution?

We are all familiar with closed-loop systems, even if we do not call them by that name. In fact, we trust our lives with some of these systems. A shortlist of some common control systems includes:

  • Cruise control on our cars
  • Thermostats
  • Industrial process control
  • Auto-pilots

There are many benefits of closed-loop systems including safety, effectiveness and efficiency. Importantly, they are designed to manage complex, uncertain systems. Very relevant in clinical situations, closed-loop systems will become “force multipliers”: allowing time-constrained professionals to focus on the important aspects of care requiring human expertise and caring.

Closed-loop systems in healthcare will be integral components of autonomous care systems.

There are specific challenges for closed-loop control in critical care, which we are addressing in the CLIP solution. These are all soluble, and well worth solving to improve patient outcomes:

  • Quality, reliability and information content of input signals
  • Choice of target variables
  • Selection of target variables and values
  • Robust controller algorithms that cope with physiological nonlinearity and variability, and adjust to changing patient state
  • “Although smart pumps have made IV infusions safer than the days of gravity drips and dial-a-flow, 23% of surveyed organizations still reported serious medication incidents in the past 24 months while using their smart pumps— 60% of those while compliant with drug libraries.”
  • Karen Giuliano, PhD
    President and CEO
    PaceSetter Associates, LLC